KMID : 0374919950160020355
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Inje Medical Journal 1995 Volume.16 No. 2 p.355 ~ p.358
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Clincial Analysis of 5 Cases of Melanosis coli
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Abstract
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Melanosis coli is the brownish black pigmentation of the colon associated with prolonged ingestion of anthraquinone compounds as laxatives. This condition is so rare that a few cases have been reported in Korea and its pathophysiology has not
been
understood clearly. Many studies have suggested that the brownish discoloration of the colon mucosa is due to accumulation of macrophage containing lipofuscin pigment.
We report 5 cases of melanosis coli histologically confirmed by colonoscopic biopsy or by operation from January, 1992 to September, 1994 in this hospital with a review of the literature.
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KEYWORD
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